Flatness of Cell Factories: A Key Factor Affecting Cell Culture Performance

Thu Jul 04 14:45:43 CST 2024

Cell factories, as multi-layered cell culture containers, are widely used for large-scale cell culture, playing a crucial role in industrial biopharmaceuticals and vaccine production. The quality of these cell factories significantly impacts cell growth, with flatness being a critical factor.

Firstly, the flatness of the cell factory is vital for cell growth. Cells require a stable environment for growth and metabolism. If the bottom surface is uneven, cells tend to accumulate in lower areas during culture, leading to uneven cell distribution. This can negatively impact cell growth and metabolism, potentially causing cell death, slowed growth, and abnormal cell morphology, ultimately affecting the experiment's progress and results.

Cell Factories

Ensuring the flatness of cell factories involves several measures. High precision in the molds used for consumables is essential, as this is the foundation for producing high-quality products. Additionally, controlling the production process is key, including the selection of materials, control of manufacturing processes, and standardization of assembly procedures. Post-assembly flatness testing is also crucial, with rigorous quality checks to ensure product conformity and flatness.

In conclusion, the flatness of cell factories is one of the critical factors influencing cell growth. To achieve optimal cell growth, it is necessary to address flatness issues through multiple measures and testing, ensuring a stable and even growth environment for cells. This approach ensures the smooth progress of cell culture experiments, providing strong support for the development of biopharmaceuticals and vaccine production.

The FAI climbed 5.9 percent year-on-year in the first 11 months of 2018, quickening from the 5.7-percent growth in Jan-Oct, the National Bureau of Statistics (NBS) said Friday in an online statement.

The key indicator of investment, dubbed a major growth driver, hit the bottom in August and has since started to rebound steadily.

In the face of emerging economic challenges home and abroad, China has stepped up efforts to stabilize investment, in particular rolling out measures to motivate private investors and channel funds into infrastructure.

Friday's data showed private investment, accounting for more than 60 percent of the total FAI, expanded by a brisk 8.7 percent.

NBS spokesperson Mao Shengyong said funds into weak economic links registered rapid increases as investment in environmental protection and agriculture jumped 42 percent and 12.5 percent respectively, much faster than the average.

In breakdown, investment in high-tech and equipment manufacturing remained vigorous with 16.1-percent and 11.6-percent increases respectively in the first 11 months. Infrastructure investment gained 3.7 percent, staying flat. Investment in property development rose 9.7 percent, also unchanged.