Characteristics and Applications of Roller Bottles

Wed Jun 26 09:44:48 CST 2024

Roller bottles are crucial tools in cell culture, playing an indispensable role in life sciences research and biotechnology industries. Their unique design and manufacturing processes allow cells to grow and proliferate in specific environments, providing essential support for scientific research.

Key Characteristics:

Wide Applicability:Roller bottles are versatile and can accommodate a variety of cell types, including both adherent and suspension cells. This wide applicability makes them suitable for culturing a range of cells, such as:

Vero Cells: Commonly used in virology and vaccine production.HEK 293 Cells: Widely used in gene expression studies and biotechnology.CAR-T Cells: Important for immunotherapy and cancer research.Myeloma Cells: Used in monoclonal antibody production.

Surface Treatment Technology:Roller bottles are often manufactured using injection blow molding, which ensures smooth and rounded bottle mouths for better sealing with caps. This process enhances the adhesion of cells to the bottle surface, reducing contamination risk and promoting uniform cell attachment, thus improving cell growth efficiency and experimental reliability.

Roller bottles

Convenient Design:The design of roller bottles considers user convenience and operational stability. For instance, 5L roller bottles feature a two-piece design that enhances product strength and increases the contact area with the rollers in roller machines, ensuring stable operation. The frosted contact area of the roller machine increases friction, reducing slippage and improving the efficiency and safety of experiments.


Cell Culture:Roller bottles are extensively used for culturing various cell types, providing a large surface area for cell growth and facilitating high-yield cell production. They are especially useful for producing cells needed in large quantities, such as for vaccine production and large-scale biological research.

Biotechnology and Pharmaceutical Production:

In biotechnology and pharmaceutical industries, roller bottles are used for producing biologics, including monoclonal antibodies, vaccines, and recombinant proteins. Their ability to support high-density cell cultures makes them ideal for these applications.

Research and Development:Roller bottles are essential in R&D labs for various applications, including drug screening, toxicology studies, and the production of viral vectors for gene therapy. Their versatility and reliability make them a staple in experimental setups.

Conclusion:The key features of roller bottles, such as their broad applicability, unique surface treatment technology, stringent production environment control, and user-friendly design, make them invaluable in life sciences research and biotechnology industries.

These characteristics ensure that Roller bottles continue to play a significant role in advancing scientific research and industrial applications.

The FAI climbed 5.9 percent year-on-year in the first 11 months of 2018, quickening from the 5.7-percent growth in Jan-Oct, the National Bureau of Statistics (NBS) said Friday in an online statement.

The key indicator of investment, dubbed a major growth driver, hit the bottom in August and has since started to rebound steadily.

In the face of emerging economic challenges home and abroad, China has stepped up efforts to stabilize investment, in particular rolling out measures to motivate private investors and channel funds into infrastructure.

Friday's data showed private investment, accounting for more than 60 percent of the total FAI, expanded by a brisk 8.7 percent.

NBS spokesperson Mao Shengyong said funds into weak economic links registered rapid increases as investment in environmental protection and agriculture jumped 42 percent and 12.5 percent respectively, much faster than the average.

In breakdown, investment in high-tech and equipment manufacturing remained vigorous with 16.1-percent and 11.6-percent increases respectively in the first 11 months. Infrastructure investment gained 3.7 percent, staying flat. Investment in property development rose 9.7 percent, also unchanged.